BDBM6392 (4-Chloro-phenyl)-{6-[5-(3-pyridin-4-yl-propylamino)pyridin-3-yl]-pyrazin-2-yl}-amine::N-(4-chlorophenyl)-6-(5-{[3-(pyridin-4-yl)propyl]amino}pyridin-3-yl)pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 24

SMILES: Clc1ccc(Nc2cncc(n2)-c2cncc(NCCCc3ccncc3)c2)cc1

InChI Key: InChIKey=YKNBMORIVLLGGL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
VEGFR-2 (KDR) (Rattus norvegicus (rat))	BDBM6392 ((4-Chloro-phenyl)-{6-[5-(3-pyridin-4-yl-propylamin...) Show SMILES Clc1ccc(Nc2cncc(n2)-c2cncc(NCCCc3ccncc3)c2)cc1 Show InChI InChI=1S/C23H21ClN6/c24-19-3-5-20(6-4-19)29-23-16-27-15-22(30-23)18-12-21(14-26-13-18)28-9-1-2-17-7-10-25-11-8-17/h3-8,10-16,28H,1-2,9H2,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 1 (CDK1) (Homo sapiens (Human))	BDBM6392 ((4-Chloro-phenyl)-{6-[5-(3-pyridin-4-yl-propylamin...) Show SMILES Clc1ccc(Nc2cncc(n2)-c2cncc(NCCCc3ccncc3)c2)cc1 Show InChI InChI=1S/C23H21ClN6/c24-19-3-5-20(6-4-19)29-23-16-27-15-22(30-23)18-12-21(14-26-13-18)28-9-1-2-17-7-10-25-11-8-17/h3-8,10-16,28H,1-2,9H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 4892-909 (2005) Article DOI: 10.1021/jm058205b BindingDB Entry DOI: 10.7270/Q2NC5ZD5
					More data for this Ligand-Target Pair