BDBM64368 MLS001096044::N-(5-chloranyl-2,4-dimethoxy-phenyl)-2-[methyl-[(2-oxidanylidene-3H-1,3-benzoxazol-6-yl)sulfonyl]amino]ethanamide::N-(5-chloro-2,4-dimethoxy-phenyl)-2-[(2-keto-3H-1,3-benzoxazol-6-yl)sulfonyl-methyl-amino]acetamide::N-(5-chloro-2,4-dimethoxyphenyl)-2-[methyl-[(2-oxo-3H-1,3-benzoxazol-6-yl)sulfonyl]amino]acetamide::SMR000631034::cid_20949400

SMILES: COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1Cl

InChI Key: InChIKey=GYVAUCNCOYTKER-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 64368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hsf1 protein (Mus musculus)	BDBM64368 (MLS001096044 | N-(5-chloranyl-2,4-dimethoxy-phenyl...) Show SMILES COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1Cl Show InChI InChI=1S/C18H18ClN3O7S/c1-22(30(25,26)10-4-5-12-16(6-10)29-18(24)21-12)9-17(23)20-13-7-11(19)14(27-2)8-15(13)28-3/h4-8H,9H2,1-3H3,(H,20,23)(H,21,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.95E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
					More data for this Ligand-Target Pair
Intestinal alkaline phosphatase (Homo sapiens (Human))	BDBM64368 (MLS001096044 | N-(5-chloranyl-2,4-dimethoxy-phenyl...) Show SMILES COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1Cl Show InChI InChI=1S/C18H18ClN3O7S/c1-22(30(25,26)10-4-5-12-16(6-10)29-18(24)21-12)9-17(23)20-13-7-11(19)14(27-2)8-15(13)28-3/h4-8H,9H2,1-3H3,(H,20,23)(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.84E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q29G5K8R
					More data for this Ligand-Target Pair
Alpi (Rattus norvegicus (Rat))	BDBM64368 (MLS001096044 | N-(5-chloranyl-2,4-dimethoxy-phenyl...) Show SMILES COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1Cl Show InChI InChI=1S/C18H18ClN3O7S/c1-22(30(25,26)10-4-5-12-16(6-10)29-18(24)21-12)9-17(23)20-13-7-11(19)14(27-2)8-15(13)28-3/h4-8H,9H2,1-3H3,(H,20,23)(H,21,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.15E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2J38R0R
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human))	BDBM64368 (MLS001096044 | N-(5-chloranyl-2,4-dimethoxy-phenyl...) Show SMILES COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1Cl Show InChI InChI=1S/C18H18ClN3O7S/c1-22(30(25,26)10-4-5-12-16(6-10)29-18(24)21-12)9-17(23)20-13-7-11(19)14(27-2)8-15(13)28-3/h4-8H,9H2,1-3H3,(H,20,23)(H,21,24)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	7.07E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2J101NV
					More data for this Ligand-Target Pair
Alkaline phosphatase placental-like (Homo sapiens (Human))	BDBM64368 (MLS001096044 | N-(5-chloranyl-2,4-dimethoxy-phenyl...) Show SMILES COc1cc(OC)c(NC(=O)CN(C)S(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1Cl Show InChI InChI=1S/C18H18ClN3O7S/c1-22(30(25,26)10-4-5-12-16(6-10)29-18(24)21-12)9-17(23)20-13-7-11(19)14(27-2)8-15(13)28-3/h4-8H,9H2,1-3H3,(H,20,23)(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.98E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2SJ1J25
					More data for this Ligand-Target Pair