null

SMILES: CCc1c(N2CCN(CC2)C(=O)c2nccc(F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(nc1Cl)C(F)(F)F)C1=CCOCC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 646454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238] (Homo sapiens (Human))	BDBM646454 (US11878973, Example 48) Show SMILES CCc1c(N2CCN(CC2)C(=O)c2nccc(F)c2O)c(=O)n2nc(nc2n1CC(=O)Nc1ccc(nc1Cl)C(F)(F)F)C1=CCOCC1 |t:48| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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