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SMILES: Cc1c(nc2c3cc(cnc3ccn12)-c1cnn(c1)C1CN(C1)C(=O)CC#N)-c1c(Cl)cccc1Cl

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651426   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 3


(Homo sapiens (Human))		BDBM651426
PNG
(US11897891, Example 41)
Show SMILES Cc1c(nc2c3cc(cnc3ccn12)-c1cnn(c1)C1CN(C1)C(=O)CC#N)-c1c(Cl)cccc1Cl |(-9.35,.49,;-7.88,-0,;-6.6,.88,;-5.35,-.03,;-5.83,-1.49,;-5.06,-2.83,;-3.52,-2.83,;-2.75,-4.16,;-3.52,-5.5,;-5.06,-5.5,;-5.83,-4.16,;-7.37,-4.16,;-8.14,-2.83,;-7.37,-1.49,;-1.21,-4.16,;-.31,-5.41,;1.16,-4.93,;1.16,-3.39,;-.31,-2.92,;2.4,-2.49,;3.93,-2.73,;4.17,-1.21,;2.65,-.97,;5.41,-.3,;5.25,1.23,;6.82,-.93,;8.07,-.02,;9.31,.88,;-6.6,2.42,;-7.93,3.19,;-9.27,2.42,;-7.93,4.73,;-6.6,5.5,;-5.27,4.73,;-5.27,3.19,;-3.93,2.42,)|
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Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN98TV
More data for this
Ligand-Target Pair