BDBM65888 (2',4'-Dimethyl-[4,5']bithiazolyl-2-yl)-pyridin-2-yl-amine::4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-pyridin-2-yl-1,3-thiazol-2-amine::4-(2,4-dimethyl-5-thiazolyl)-N-(2-pyridinyl)-2-thiazolamine::MLS001205174::SMR000524327::[4-(2,4-dimethylthiazol-5-yl)thiazol-2-yl]-(2-pyridyl)amine::cid_556143

SMILES: Cc1nc(C)c(s1)-c1csc(Nc2ccccn2)n1

InChI Key: InChIKey=QFZCXSQSNPMBIJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 65888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 4 (Homo sapiens (Human))	BDBM65888 ((2',4'-Dimethyl-[4,5']bithiazolyl-2-yl...) Show SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccccn2)n1 Show InChI InChI=1S/C13H12N4S2/c1-8-12(19-9(2)15-8)10-7-18-13(16-10)17-11-5-3-4-6-14-11/h3-7H,1-2H3,(H,14,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi& Co., Ltd. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant TRPV4 expressed in CHO-K1 cells assessed as blockade of 1000 nM 4alphaPDD-induced calcium mobilization by FL...				Bioorg Med Chem Lett 26: 4930-4935 (2016) Article DOI: 10.1016/j.bmcl.2016.09.013 BindingDB Entry DOI: 10.7270/Q2BC41H5
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv7.2 (Rattus norvegicus)	BDBM65888 ((2',4'-Dimethyl-[4,5']bithiazolyl-2-yl...) Show SMILES Cc1nc(C)c(s1)-c1csc(Nc2ccccn2)n1 Show InChI InChI=1S/C13H12N4S2/c1-8-12(19-9(2)15-8)10-7-18-13(16-10)17-11-5-3-4-6-14-11/h3-7H,1-2H3,(H,14,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.15E+5	n/a	n/a	n/a	n/a
Johns Hopkins Ion Channel Center Curated by PubChem BioAssay					Assay Description BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q20000JS
					More data for this Ligand-Target Pair