BDBM66187 5,5-Dimethyl-2-thioxo-2,3,5,6-tetrahydro-1H-benzo[h]quinazolin-4-one::5,5-dimethyl-2-sulfanylidene-1,6-dihydrobenzo[h]quinazolin-4-one::5,5-dimethyl-2-thioxo-1,6-dihydrobenzo[h]quinazolin-4-one::MLS001211957::SMR000505168::cid_713572

SMILES: CC1(C)Cc2ccccc2-c2[nH]c(=S)[nH]c(=O)c12

InChI Key: InChIKey=XMYDQZMDMBKIEW-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 66187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM66187 (5,5-Dimethyl-2-thioxo-2,3,5,6-tetrahydro-1H-benzo[...) Show SMILES CC1(C)Cc2ccccc2-c2[nH]c(=S)[nH]c(=O)c12 Show InChI InChI=1S/C14H14N2OS/c1-14(2)7-8-5-3-4-6-9(8)11-10(14)12(17)16-13(18)15-11/h3-6H,7H2,1-2H3,(H2,15,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2D21W22
					More data for this Ligand-Target Pair
nuclear receptor corepressor 2 isoform 2 (Homo sapiens (Human))	BDBM66187 (5,5-Dimethyl-2-thioxo-2,3,5,6-tetrahydro-1H-benzo[...) Show SMILES CC1(C)Cc2ccccc2-c2[nH]c(=S)[nH]c(=O)c12 Show InChI InChI=1S/C14H14N2OS/c1-14(2)7-8-5-3-4-6-9(8)11-10(14)12(17)16-13(18)15-11/h3-6H,7H2,1-2H3,(H2,15,16,17,18)	PDB MMDB B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q28914BQ
					More data for this Ligand-Target Pair
Prion protein (Homo sapiens (Human))	BDBM66187 (5,5-Dimethyl-2-thioxo-2,3,5,6-tetrahydro-1H-benzo[...) Show SMILES CC1(C)Cc2ccccc2-c2[nH]c(=S)[nH]c(=O)c12 Show InChI InChI=1S/C14H14N2OS/c1-14(2)7-8-5-3-4-6-9(8)11-10(14)12(17)16-13(18)15-11/h3-6H,7H2,1-2H3,(H2,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2HM573M
					More data for this Ligand-Target Pair
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM66187 (5,5-Dimethyl-2-thioxo-2,3,5,6-tetrahydro-1H-benzo[...) Show SMILES CC1(C)Cc2ccccc2-c2[nH]c(=S)[nH]c(=O)c12 Show InChI InChI=1S/C14H14N2OS/c1-14(2)7-8-5-3-4-6-9(8)11-10(14)12(17)16-13(18)15-11/h3-6H,7H2,1-2H3,(H2,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2FN14T0
					More data for this Ligand-Target Pair
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM66187 (5,5-Dimethyl-2-thioxo-2,3,5,6-tetrahydro-1H-benzo[...) Show SMILES CC1(C)Cc2ccccc2-c2[nH]c(=S)[nH]c(=O)c12 Show InChI InChI=1S/C14H14N2OS/c1-14(2)7-8-5-3-4-6-9(8)11-10(14)12(17)16-13(18)15-11/h3-6H,7H2,1-2H3,(H2,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q29W0D3P
					More data for this Ligand-Target Pair
HIV-1 B HXB2-LAI-IIIB-BRU (Human immunodeficiency virus type 1 group M subtyp...)	BDBM66187 (5,5-Dimethyl-2-thioxo-2,3,5,6-tetrahydro-1H-benzo[...) Show SMILES CC1(C)Cc2ccccc2-c2[nH]c(=S)[nH]c(=O)c12 Show InChI InChI=1S/C14H14N2OS/c1-14(2)7-8-5-3-4-6-9(8)11-10(14)12(17)16-13(18)15-11/h3-6H,7H2,1-2H3,(H2,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2KD1WJB
					More data for this Ligand-Target Pair