null

SMILES: Cc1cc(C)cc(NC(=O)C(=C\c2cn(CC(=O)NCc3ccco3)c3ccccc23)\C#N)c1

InChI Key: InChIKey=IUXJEXGEWOOMJH-DEDYPNTBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 66418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 11 (Homo sapiens (Human))	BDBM66418 ((E)-2-cyano-N-(3,5-dimethylphenyl)-3-[1-[2-(2-fura...) Show SMILES Cc1cc(C)cc(NC(=O)C(=C\c2cn(CC(=O)NCc3ccco3)c3ccccc23)\C#N)c1 Show InChI InChI=1S/C27H24N4O3/c1-18-10-19(2)12-22(11-18)30-27(33)20(14-28)13-21-16-31(25-8-4-3-7-24(21)25)17-26(32)29-15-23-6-5-9-34-23/h3-13,16H,15,17H2,1-2H3,(H,29,32)(H,30,33)/b20-13+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.65E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24J0CKJ
					More data for this Ligand-Target Pair
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM66418 ((E)-2-cyano-N-(3,5-dimethylphenyl)-3-[1-[2-(2-fura...) Show SMILES Cc1cc(C)cc(NC(=O)C(=C\c2cn(CC(=O)NCc3ccco3)c3ccccc23)\C#N)c1 Show InChI InChI=1S/C27H24N4O3/c1-18-10-19(2)12-22(11-18)30-27(33)20(14-28)13-21-16-31(25-8-4-3-7-24(21)25)17-26(32)29-15-23-6-5-9-34-23/h3-13,16H,15,17H2,1-2H3,(H,29,32)(H,30,33)/b20-13+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28C9TQN
					More data for this Ligand-Target Pair
X-box-binding protein 1 (Homo sapiens (Human))	BDBM66418 ((E)-2-cyano-N-(3,5-dimethylphenyl)-3-[1-[2-(2-fura...) Show SMILES Cc1cc(C)cc(NC(=O)C(=C\c2cn(CC(=O)NCc3ccco3)c3ccccc23)\C#N)c1 Show InChI InChI=1S/C27H24N4O3/c1-18-10-19(2)12-22(11-18)30-27(33)20(14-28)13-21-16-31(25-8-4-3-7-24(21)25)17-26(32)29-15-23-6-5-9-34-23/h3-13,16H,15,17H2,1-2H3,(H,29,32)(H,30,33)/b20-13+	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CGB
					More data for this Ligand-Target Pair
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM66418 ((E)-2-cyano-N-(3,5-dimethylphenyl)-3-[1-[2-(2-fura...) Show SMILES Cc1cc(C)cc(NC(=O)C(=C\c2cn(CC(=O)NCc3ccco3)c3ccccc23)\C#N)c1 Show InChI InChI=1S/C27H24N4O3/c1-18-10-19(2)12-22(11-18)30-27(33)20(14-28)13-21-16-31(25-8-4-3-7-24(21)25)17-26(32)29-15-23-6-5-9-34-23/h3-13,16H,15,17H2,1-2H3,(H,29,32)(H,30,33)/b20-13+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PC30VZ
					More data for this Ligand-Target Pair