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SMILES: CCOC(=O)Cc1csc(N=Cc2c(O)n(-c3ccc(C)c(C)c3)c(=O)c3ccccc23)n1

InChI Key: InChIKey=JOQRWJPVRRWIHP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 66438   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bcl-2-like protein 11


(Homo sapiens (Human))		BDBM66438
PNG
((2-{[2-(3,4-Dimethyl-phenyl)-1,3-dioxo-2,3-dihydro...)
Show SMILES CCOC(=O)Cc1csc(N=Cc2c(O)n(-c3ccc(C)c(C)c3)c(=O)c3ccccc23)n1 |w:10.9|
Show InChI InChI=1S/C25H23N3O4S/c1-4-32-22(29)12-17-14-33-25(27-17)26-13-21-19-7-5-6-8-20(19)23(30)28(24(21)31)18-10-9-15(2)16(3)11-18/h5-11,13-14,31H,4,12H2,1-3H3
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PC cid
PC sid
UniChem

Similars
PCBioAssay
n/an/an/an/a 9.23E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair