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SMILES: Oc1ccc2cccc(NC(=O)Nc3ccccc3)c2c1

InChI Key: InChIKey=UUAPFBCLZLDKHG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C] (Homo sapiens (Human))	BDBM6646 (3-(7-hydroxynaphthalen-1-yl)-1-phenylurea | Diaryl...) Show SMILES Oc1ccc2cccc(NC(=O)Nc3ccccc3)c2c1 Show InChI InChI=1S/C17H14N2O2/c20-14-10-9-12-5-4-8-16(15(12)11-14)19-17(21)18-13-6-2-1-3-7-13/h1-11,20H,(H2,18,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	30
Banyu Tsukuba Research Institute					Assay Description In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...				J Med Chem 44: 4615-27 (2001) Article DOI: 10.1021/jm0103256 BindingDB Entry DOI: 10.7270/Q2736P3Q
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM6646 (3-(7-hydroxynaphthalen-1-yl)-1-phenylurea | Diaryl...) Show SMILES Oc1ccc2cccc(NC(=O)Nc3ccccc3)c2c1 Show InChI InChI=1S/C17H14N2O2/c20-14-10-9-12-5-4-8-16(15(12)11-14)19-17(21)18-13-6-2-1-3-7-13/h1-11,20H,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Yakuhin, Ltd Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-i...				Bioorg Med Chem Lett 21: 3354-7 (2011) Article DOI: 10.1016/j.bmcl.2011.04.013 BindingDB Entry DOI: 10.7270/Q2NG4QXN
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM6646 (3-(7-hydroxynaphthalen-1-yl)-1-phenylurea | Diaryl...) Show SMILES Oc1ccc2cccc(NC(=O)Nc3ccccc3)c2c1 Show InChI InChI=1S/C17H14N2O2/c20-14-10-9-12-5-4-8-16(15(12)11-14)19-17(21)18-13-6-2-1-3-7-13/h1-11,20H,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Yakuhin, Ltd Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin...				Bioorg Med Chem Lett 21: 3354-7 (2011) Article DOI: 10.1016/j.bmcl.2011.04.013 BindingDB Entry DOI: 10.7270/Q2NG4QXN
					More data for this Ligand-Target Pair