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SMILES: CCCCC1CCC(CC1)C(=O)N(CC(C)C)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O

InChI Key: InChIKey=WXCYLYXOCBLNNC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 66972   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bcl-2-like protein 11


(Homo sapiens (Human))		BDBM66972
PNG
(MLS001079562 | N-(6-amino-1-benzyl-2,4-diketo-pyri...)
Show SMILES CCCCC1CCC(CC1)C(=O)N(CC(C)C)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O |(6.27,9.42,;5.28,8.24,;5.8,6.79,;4.81,5.61,;5.34,4.16,;4.35,2.98,;4.88,1.54,;6.39,1.27,;7.38,2.45,;6.86,3.9,;6.92,-.18,;8.25,.59,;6.92,-1.72,;5.59,-2.49,;4.07,-2.76,;3.54,-4.2,;3.08,-1.58,;8.25,-2.49,;8.25,-4.03,;6.92,-4.8,;9.59,-4.8,;9.59,-6.34,;10.92,-7.11,;12.26,-6.34,;13.59,-7.11,;13.59,-8.65,;12.26,-9.42,;10.92,-8.65,;10.92,-4.03,;12.26,-4.8,;10.92,-2.49,;9.59,-1.72,;9.59,-.18,)|
Show InChI InChI=1S/C26H38N4O3/c1-4-5-9-19-12-14-21(15-13-19)25(32)29(16-18(2)3)22-23(27)30(26(33)28-24(22)31)17-20-10-7-6-8-11-20/h6-8,10-11,18-19,21H,4-5,9,12-17,27H2,1-3H3,(H,28,31,33)
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PC cid
PC sid
UniChem

Similars
PCBioAssay
n/an/an/an/a 5.65E+3n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...

PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair