BDBM68227 Thiazolidinone core, 21

SMILES: OC(=O)C(Cc1ccccc1)N1C(=S)S\C(=C/c2cccc(Cl)c2)C1=O

InChI Key: InChIKey=OEPHOBCYNPQTQP-WJDWOHSUSA-N

Data: 1 IC50  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 68227   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uridine 5'-diphosphate-galactopyranose mutase (UGM) (Mycobacterium tuberculosis H37Rv)	BDBM68227 (Thiazolidinone core, 21) Show SMILES OC(=O)C(Cc1ccccc1)N1C(=S)S\C(=C/c2cccc(Cl)c2)C1=O Show InChI InChI=1S/C19H14ClNO3S2/c20-14-8-4-7-13(9-14)11-16-17(22)21(19(25)26-16)15(18(23)24)10-12-5-2-1-3-6-12/h1-9,11,15H,10H2,(H,23,24)/b16-11-	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	1.60E+4	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison					Assay Description To access the ability of compounds to inhibit the catalytic activity of UGM, an HPLC assay was employed. Inhibition constants were determined by mon...				Chem Biol 13: 825-37 (2006) Article DOI: 10.1016/j.chembiol.2006.06.007 BindingDB Entry DOI: 10.7270/Q2DV1HB1
					More data for this Ligand-Target Pair
UDP-galactopyranose mutase (Klebsiella pneumoniae)	BDBM68227 (Thiazolidinone core, 21) Show SMILES OC(=O)C(Cc1ccccc1)N1C(=S)S\C(=C/c2cccc(Cl)c2)C1=O Show InChI InChI=1S/C19H14ClNO3S2/c20-14-8-4-7-13(9-14)11-16-17(22)21(19(25)26-16)15(18(23)24)10-12-5-2-1-3-6-12/h1-9,11,15H,10H2,(H,23,24)/b16-11-	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.13E+4	n/a	n/a	n/a	n/a	n/a
University of Wisconsin-Madison					Assay Description To access the ability of compounds to inhibit the catalytic activity of UGM, an HPLC assay was employed. Inhibition constants were determined by mon...				Chem Biol 13: 825-37 (2006) Article DOI: 10.1016/j.chembiol.2006.06.007 BindingDB Entry DOI: 10.7270/Q2DV1HB1
					More data for this Ligand-Target Pair