BDBM68332 7-(4-fluorophenyl)-5-methyl-3-phenyl-pyrazolo[1,5-a]pyrimidine::7-(4-fluorophenyl)-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidine::SR-03000000931-1::cid_42640807
SMILES: Cc1cc(-c2ccc(F)cc2)n2ncc(-c3ccccc3)c2n1
InChI Key: InChIKey=CXYQLDKRLAPLDZ-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
STAT3 (Homo sapiens (Human)) | BDBM68332 (7-(4-fluorophenyl)-5-methyl-3-phenyl-pyrazolo[1,5-...) | GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >5.57E+3 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BV7F28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription Factor STAT1 (Homo sapiens (Human)) | BDBM68332 (7-(4-fluorophenyl)-5-methyl-3-phenyl-pyrazolo[1,5-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 64.3 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2R49P7N | |||||||||||
More data for this Ligand-Target Pair |