BDBM7116 2-[4-(3-Benzyl-2-oxoimidazolidin-1-yl)phenyl]-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide::3-Aminopyrazole deriv. 29

SMILES: CC(C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)N1CCN(Cc2ccccc2)C1=O

InChI Key: InChIKey=BYBNOEUBQBNKNC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 2 (CDK2) (Homo sapiens (Human))	BDBM7116 (2-[4-(3-Benzyl-2-oxoimidazolidin-1-yl)phenyl]-N-(5...) Show SMILES CC(C(=O)Nc1cc(n[nH]1)C1CC1)c1ccc(cc1)N1CCN(Cc2ccccc2)C1=O Show InChI InChI=1S/C25H27N5O2/c1-17(24(31)26-23-15-22(27-28-23)20-7-8-20)19-9-11-21(12-10-19)30-14-13-29(25(30)32)16-18-5-3-2-4-6-18/h2-6,9-12,15,17,20H,7-8,13-14,16H2,1H3,(H2,26,27,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nerviano Medical Sciences					Assay Description The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...				J Med Chem 48: 2944-56 (2005) Article DOI: 10.1021/jm0408870 BindingDB Entry DOI: 10.7270/Q2WQ020R
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