null

SMILES: Cc1nnc(Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc2ccccc2Cl)s1

InChI Key: InChIKey=SMDITLRYNUIBJO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 71627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Importin subunit alpha-1 (Homo sapiens (Human))	BDBM71627 (7-(2-Chloro-benzyl)-1,3-dimethyl-8-(5-methyl-[1,3,...) Show SMILES Cc1nnc(Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc2ccccc2Cl)s1 Show InChI InChI=1S/C17H15ClN6O2S2/c1-9-20-21-16(27-9)28-15-19-13-12(14(25)23(3)17(26)22(13)2)24(15)8-10-6-4-5-7-11(10)18/h4-7H,8H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair
Heat shock factor protein 1 (Mus musculus)	BDBM71627 (7-(2-Chloro-benzyl)-1,3-dimethyl-8-(5-methyl-[1,3,...) Show SMILES Cc1nnc(Sc2nc3n(C)c(=O)n(C)c(=O)c3n2Cc2ccccc2Cl)s1 Show InChI InChI=1S/C17H15ClN6O2S2/c1-9-20-21-16(27-9)28-15-19-13-12(14(25)23(3)17(26)22(13)2)24(15)8-10-6-4-5-7-11(10)18/h4-7H,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>2.60E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK
					More data for this Ligand-Target Pair