null
SMILES: Cc1cc(=O)oc2cc(N)ccc12
InChI Key: InChIKey=GLNDAGDHSLMOKX-UHFFFAOYSA-N
PDB links: 20 PDB IDs match this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM71742 (7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | 5.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 1 after 6 hrs by stop-flow CO2 hydration assay | Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM71742 (7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | 7.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 9 after 6 hrs by stop-flow CO2 hydration assay | Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM71742 (7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | 9.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 12 after 6 hrs by stop-flow CO2 hydration assay | Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM71742 (7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human carbonic anhydrase 2 after 6 hrs by stop-flow CO2 hydration assay | Bioorg Med Chem 20: 2266-73 (2012) Article DOI: 10.1016/j.bmc.2012.02.014 BindingDB Entry DOI: 10.7270/Q2P26ZK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heat shock factor protein 1 (Mus musculus) | BDBM71742 (7-amino-4-methyl-1-benzopyran-2-one | 7-amino-4-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem | PCBioAssay | n/a | n/a | n/a | n/a | >2.60E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK | |||||||||||
More data for this Ligand-Target Pair |