BDBM7437 2-(2-Dimethylaminoethyl)-5-methyl-1,2-di-hydro-6H-2,4,6-triaza-cyclopenta[c]fluoren-3-one::4-[2-(dimethylamino)ethyl]-8-methyl-4,7,10-triazatetracyclo[7.7.0.0^{2,6}.0^{11,16}]hexadeca-1(9),2(6),7,11(16),12,14-hexaen-5-one::pyrrolo-beta-carboline deriv. 35

SMILES: CN(C)CCN1Cc2c(nc(C)c3[nH]c4ccccc4c23)C1=O

InChI Key: InChIKey=AWMJXZAMADBKLJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Synthase Kinase-3, beta (Porcine)	BDBM7437 (2-(2-Dimethylaminoethyl)-5-methyl-1,2-di-hydro-6H-...) Show SMILES CN(C)CCN1Cc2c(nc(C)c3[nH]c4ccccc4c23)C1=O Show InChI InChI=1S/C18H20N4O/c1-11-16-15(12-6-4-5-7-14(12)20-16)13-10-22(9-8-21(2)3)18(23)17(13)19-11/h4-7,20H,8-10H2,1-3H3	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	30
CNRS					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem 13: 2263-83 (2005) Article DOI: 10.1016/j.bmc.2004.12.045 BindingDB Entry DOI: 10.7270/Q2VQ30VZ
					More data for this Ligand-Target Pair