BDBM74475 3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-1,3-thiazolidin-4-one hydrochloride::3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-1,3-thiazolidin-4-one;hydrochloride::3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-4-thiazolidinone;hydrochloride::3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)thiazolidin-4-one;hydrochloride::MLS000533188::SMR000140626::cid_2860932

SMILES: COc1ccc(cc1)C1SCC(=O)N1CCCN(C)C

InChI Key: InChIKey=CPILGZZHWWNMTE-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 74475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM74475 (3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-1,...) Show SMILES COc1ccc(cc1)C1SCC(=O)N1CCCN(C)C Show InChI InChI=1S/C15H22N2O2S/c1-16(2)9-4-10-17-14(18)11-20-15(17)12-5-7-13(19-3)8-6-12/h5-8,15H,4,9-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24748BK
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM74475 (3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-1,...) Show SMILES COc1ccc(cc1)C1SCC(=O)N1CCCN(C)C Show InChI InChI=1S/C15H22N2O2S/c1-16(2)9-4-10-17-14(18)11-20-15(17)12-5-7-13(19-3)8-6-12/h5-8,15H,4,9-11H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli Federico II Curated by ChEMBL					Assay Description In vitro for histamine H1 receptor antagonist activity against histamine-induced contractions on isolated guinea pig ileum				J Med Chem 35: 2910-2 (1992) BindingDB Entry DOI: 10.7270/Q2XK8G4G
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM74475 (3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-1,...) Show SMILES COc1ccc(cc1)C1SCC(=O)N1CCCN(C)C Show InChI InChI=1S/C15H22N2O2S/c1-16(2)9-4-10-17-14(18)11-20-15(17)12-5-7-13(19-3)8-6-12/h5-8,15H,4,9-11H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CR5RTC
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM74475 (3-[3-(dimethylamino)propyl]-2-(4-methoxyphenyl)-1,...) Show SMILES COc1ccc(cc1)C1SCC(=O)N1CCCN(C)C Show InChI InChI=1S/C15H22N2O2S/c1-16(2)9-4-10-17-14(18)11-20-15(17)12-5-7-13(19-3)8-6-12/h5-8,15H,4,9-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VQ314Z
					More data for this Ligand-Target Pair