BDBM74479 2-(2-Chloro-acetylamino)-2-[4-(1-ethoxycarbonyl-2,2,2-trifluoro-1-hydroxy-ethyl)-phenylamino]-3,3,3-trifluoro-propionic acid ethyl ester::2-[4-[[1-carbethoxy-1-[(2-chloroacetyl)amino]-2,2,2-trifluoro-ethyl]amino]phenyl]-3,3,3-trifluoro-2-hydroxy-propionic acid ethyl ester::2-[4-[[2-[(2-chloro-1-oxoethyl)amino]-3-ethoxy-1,1,1-trifluoro-3-oxopropan-2-yl]amino]phenyl]-3,3,3-trifluoro-2-hydroxypropanoic acid ethyl ester::MLS000589015::SMR000212628::cid_3351058::ethyl 2-[4-[[2-(2-chloranylethanoylamino)-3-ethoxy-1,1,1-tris(fluoranyl)-3-oxidanylidene-propan-2-yl]amino]phenyl]-3,3,3-tris(fluoranyl)-2-oxidanyl-propanoate::ethyl 2-[4-[[2-[(2-chloroacetyl)amino]-3-ethoxy-1,1,1-trifluoro-3-oxopropan-2-yl]amino]phenyl]-3,3,3-trifluoro-2-hydroxypropanoate
SMILES: CCOC(=O)C(O)(c1ccc(NC(NC(=O)CCl)(C(=O)OCC)C(F)(F)F)cc1)C(F)(F)F
InChI Key: InChIKey=INXKFUXJUKWNRA-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human)) | BDBM74479 (2-(2-Chloro-acetylamino)-2-[4-(1-ethoxycarbonyl-2,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >7.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24748BK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human)) | BDBM74479 (2-(2-Chloro-acetylamino)-2-[4-(1-ethoxycarbonyl-2,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >7.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CR5RTC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein phosphatase non-receptor type 7 (Homo sapiens (Human)) | BDBM74479 (2-(2-Chloro-acetylamino)-2-[4-(1-ethoxycarbonyl-2,...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | PCBioAssay | n/a | n/a | >7.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VQ314Z | |||||||||||
More data for this Ligand-Target Pair |