BDBM74496 2-[[4-(2,4-dimethylphenyl)-3-propoxycarbonyl-2-thienyl]carbamoyl]-7-oxabicyclo[2.2.1]heptane-3-carboxylic acid::2-[[4-(2,4-dimethylphenyl)-3-propoxycarbonyl-thiophen-2-yl]carbamoyl]-7-oxabicyclo[2.2.1]heptane-3-carboxylic acid::2-[[4-(2,4-dimethylphenyl)-3-propoxycarbonylthiophen-2-yl]carbamoyl]-7-oxabicyclo[2.2.1]heptane-3-carboxylic acid::2-[[[4-(2,4-dimethylphenyl)-3-[oxo(propoxy)methyl]-2-thiophenyl]amino]-oxomethyl]-7-oxabicyclo[2.2.1]heptane-3-carboxylic acid::3-({[4-(2,4-dimethylphenyl)-3-(propoxycarbonyl)-2-thienyl]amino}carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid::MLS000704999::SMR000231221::cid_4187185

SMILES: [H]C12CCC([H])(O1)C(C2C(O)=O)C(=O)Nc1scc(c1C(=O)OCCC)-c1ccc(C)cc1C

InChI Key: InChIKey=NJNHMQHWMOVCTF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 74496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM74496 (2-[[4-(2,4-dimethylphenyl)-3-propoxycarbonyl-2-thi...) Show SMILES [H]C12CCC([H])(O1)C(C2C(O)=O)C(=O)Nc1scc(c1C(=O)OCCC)-c1ccc(C)cc1C |TLB:12:7:6:3.2,THB:9:8:6:3.2| Show InChI InChI=1S/C24H27NO6S/c1-4-9-30-24(29)18-15(14-6-5-12(2)10-13(14)3)11-32-22(18)25-21(26)19-16-7-8-17(31-16)20(19)23(27)28/h5-6,10-11,16-17,19-20H,4,7-9H2,1-3H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24748BK
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM74496 (2-[[4-(2,4-dimethylphenyl)-3-propoxycarbonyl-2-thi...) Show SMILES [H]C12CCC([H])(O1)C(C2C(O)=O)C(=O)Nc1scc(c1C(=O)OCCC)-c1ccc(C)cc1C |TLB:12:7:6:3.2,THB:9:8:6:3.2| Show InChI InChI=1S/C24H27NO6S/c1-4-9-30-24(29)18-15(14-6-5-12(2)10-13(14)3)11-32-22(18)25-21(26)19-16-7-8-17(31-16)20(19)23(27)28/h5-6,10-11,16-17,19-20H,4,7-9H2,1-3H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CR5RTC
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Homo sapiens (Human))	BDBM74496 (2-[[4-(2,4-dimethylphenyl)-3-propoxycarbonyl-2-thi...) Show SMILES [H]C12CCC([H])(O1)C(C2C(O)=O)C(=O)Nc1scc(c1C(=O)OCCC)-c1ccc(C)cc1C |TLB:12:7:6:3.2,THB:9:8:6:3.2| Show InChI InChI=1S/C24H27NO6S/c1-4-9-30-24(29)18-15(14-6-5-12(2)10-13(14)3)11-32-22(18)25-21(26)19-16-7-8-17(31-16)20(19)23(27)28/h5-6,10-11,16-17,19-20H,4,7-9H2,1-3H3,(H,25,26)(H,27,28)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VQ314Z
					More data for this Ligand-Target Pair