BDBM74532 4-[3-(3,4-dimethoxyphenyl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-4-oxidanylidene-butanoic acid::4-[3-(3,4-dimethoxyphenyl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-4-oxobutanoic acid::4-[5-(3,4-Dimethoxy-phenyl)-3-p-tolyl-4,5-dihydro-pyrazol-1-yl]-4-oxo-butyric acid::4-[5-(3,4-dimethoxyphenyl)-3-(p-tolyl)-2-pyrazolin-1-yl]-4-keto-butyric acid::MLS001211891::SMR000516942::cid_3132765

SMILES: COc1ccc(cc1OC)C1CC(=NN1C(=O)CCC(O)=O)c1ccc(C)cc1

InChI Key: InChIKey=VLKCLPMMZZBNDW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 74532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM74532 (4-[3-(3,4-dimethoxyphenyl)-5-(4-methylphenyl)-3,4-...) Show SMILES COc1ccc(cc1OC)C1CC(=NN1C(=O)CCC(O)=O)c1ccc(C)cc1 |c:13| Show InChI InChI=1S/C22H24N2O5/c1-14-4-6-15(7-5-14)17-13-18(24(23-17)21(25)10-11-22(26)27)16-8-9-19(28-2)20(12-16)29-3/h4-9,12,18H,10-11,13H2,1-3H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24748BK
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM74532 (4-[3-(3,4-dimethoxyphenyl)-5-(4-methylphenyl)-3,4-...) Show SMILES COc1ccc(cc1OC)C1CC(=NN1C(=O)CCC(O)=O)c1ccc(C)cc1 |c:13| Show InChI InChI=1S/C22H24N2O5/c1-14-4-6-15(7-5-14)17-13-18(24(23-17)21(25)10-11-22(26)27)16-8-9-19(28-2)20(12-16)29-3/h4-9,12,18H,10-11,13H2,1-3H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CR5RTC
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM74532 (4-[3-(3,4-dimethoxyphenyl)-5-(4-methylphenyl)-3,4-...) Show SMILES COc1ccc(cc1OC)C1CC(=NN1C(=O)CCC(O)=O)c1ccc(C)cc1 |c:13| Show InChI InChI=1S/C22H24N2O5/c1-14-4-6-15(7-5-14)17-13-18(24(23-17)21(25)10-11-22(26)27)16-8-9-19(28-2)20(12-16)29-3/h4-9,12,18H,10-11,13H2,1-3H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VQ314Z
					More data for this Ligand-Target Pair