BDBM74536 2-[3-(3-fluoranyl-4-methyl-phenyl)-2,4-bis(oxidanylidene)thieno[3,2-d]pyrimidin-1-yl]-N-(oxolan-2-ylmethyl)ethanamide::2-[3-(3-fluoro-4-methyl-phenyl)-2,4-diketo-thieno[3,2-d]pyrimidin-1-yl]-N-(tetrahydrofurfuryl)acetamide::2-[3-(3-fluoro-4-methylphenyl)-2,4-dioxo-1-thieno[3,2-d]pyrimidinyl]-N-(2-oxolanylmethyl)acetamide::2-[3-(3-fluoro-4-methylphenyl)-2,4-dioxothieno[3,2-d]pyrimidin-1-yl]-N-(oxolan-2-ylmethyl)acetamide::MLS000950328::SMR000621722::cid_6621355

SMILES: Cc1ccc(cc1F)-n1c(=O)n(CC(=O)NCC2CCCO2)c2ccsc2c1=O

InChI Key: InChIKey=NFENTEADBQHIII-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 74536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM74536 (2-[3-(3-fluoranyl-4-methyl-phenyl)-2,4-bis(oxidany...) Show SMILES Cc1ccc(cc1F)-n1c(=O)n(CC(=O)NCC2CCCO2)c2ccsc2c1=O Show InChI InChI=1S/C20H20FN3O4S/c1-12-4-5-13(9-15(12)21)24-19(26)18-16(6-8-29-18)23(20(24)27)11-17(25)22-10-14-3-2-7-28-14/h4-6,8-9,14H,2-3,7,10-11H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24748BK
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM74536 (2-[3-(3-fluoranyl-4-methyl-phenyl)-2,4-bis(oxidany...) Show SMILES Cc1ccc(cc1F)-n1c(=O)n(CC(=O)NCC2CCCO2)c2ccsc2c1=O Show InChI InChI=1S/C20H20FN3O4S/c1-12-4-5-13(9-15(12)21)24-19(26)18-16(6-8-29-18)23(20(24)27)11-17(25)22-10-14-3-2-7-28-14/h4-6,8-9,14H,2-3,7,10-11H2,1H3,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CR5RTC
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 7 (Homo sapiens (Human))	BDBM74536 (2-[3-(3-fluoranyl-4-methyl-phenyl)-2,4-bis(oxidany...) Show SMILES Cc1ccc(cc1F)-n1c(=O)n(CC(=O)NCC2CCCO2)c2ccsc2c1=O Show InChI InChI=1S/C20H20FN3O4S/c1-12-4-5-13(9-15(12)21)24-19(26)18-16(6-8-29-18)23(20(24)27)11-17(25)22-10-14-3-2-7-28-14/h4-6,8-9,14H,2-3,7,10-11H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VQ314Z
					More data for this Ligand-Target Pair