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SMILES: Nc1[nH]c(=S)c(C#N)c(-c2ccccc2)c1C#N

InChI Key: InChIKey=KTPFGSXXUDJFFQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 74685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Importin subunit alpha-1 (Homo sapiens (Human))	BDBM74685 (2-amino-4-phenyl-6-sulfanylidene-1H-pyridine-3,5-d...) Show SMILES Nc1[nH]c(=S)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C13H8N4S/c14-6-9-11(8-4-2-1-3-5-8)10(7-15)13(18)17-12(9)16/h1-5H,(H3,16,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM74685 (2-amino-4-phenyl-6-sulfanylidene-1H-pyridine-3,5-d...) Show SMILES Nc1[nH]c(=S)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C13H8N4S/c14-6-9-11(8-4-2-1-3-5-8)10(7-15)13(18)17-12(9)16/h1-5H,(H3,16,17,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Química Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of equine serum BuChE after 10 mins by Ellman's method				Bioorg Med Chem 18: 5861-72 (2010) Article DOI: 10.1016/j.bmc.2010.06.095 BindingDB Entry DOI: 10.7270/Q23J3D5D
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM74685 (2-amino-4-phenyl-6-sulfanylidene-1H-pyridine-3,5-d...) Show SMILES Nc1[nH]c(=S)c(C#N)c(-c2ccccc2)c1C#N Show InChI InChI=1S/C13H8N4S/c14-6-9-11(8-4-2-1-3-5-8)10(7-15)13(18)17-12(9)16/h1-5H,(H3,16,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratorio de Radicales Libres y Química Computacional (IQOG, CSIC) Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE after 10 mins by Ellman's method				Bioorg Med Chem 18: 5861-72 (2010) Article DOI: 10.1016/j.bmc.2010.06.095 BindingDB Entry DOI: 10.7270/Q23J3D5D
					More data for this Ligand-Target Pair