BDBM75024 2-hydroxy-4-keto-1-propyl-2-pyrroline-3-carbonitrile::4-hydroxy-2-oxo-1-propyl-2,5-dihydro-1H-pyrrole-3-carbonitrile::5-hydroxy-3-oxo-1-propyl-2H-pyrrole-4-carbonitrile::5-oxidanyl-3-oxidanylidene-1-propyl-2H-pyrrole-4-carbonitrile::MLS000721839::SMR000336987::cid_1475708

SMILES: CCCn1cc(O)c(C#N)c1O

InChI Key: InChIKey=MCLCFAXHKXTILH-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75024   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM75024 (2-hydroxy-4-keto-1-propyl-2-pyrroline-3-carbonitri...) Show SMILES CCCn1cc(O)c(C#N)c1O Show InChI InChI=1S/C8H10N2O2/c1-2-3-10-5-7(11)6(4-9)8(10)12/h5,11-12H,2-3H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair