null

SMILES: Nc1nc(Cl)c2ncn(C3CC=CC3)c2n1

InChI Key: InChIKey=QOQFUVAAAFKRRL-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM7503 (2,6,9-Trisubstituted purine deriv. 3f | 2-Amino-6-...) Show SMILES Nc1nc(Cl)c2ncn(C3CC=CC3)c2n1 |c:11| Show InChI InChI=1S/C10H10ClN5/c11-8-7-9(15-10(12)14-8)16(5-13-7)6-3-1-2-4-6/h1-2,5-6H,3-4H2,(H2,12,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.2	30
Institut Curie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem 7: 1281-93 (1999) Article DOI: 10.1016/S0968-0896(99)00064-4 BindingDB Entry DOI: 10.7270/Q23776X6
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Marthasterias glacialis (starfish))	BDBM7503 (2,6,9-Trisubstituted purine deriv. 3f | 2-Amino-6-...) Show SMILES Nc1nc(Cl)c2ncn(C3CC=CC3)c2n1 |c:11| Show InChI InChI=1S/C10H10ClN5/c11-8-7-9(15-10(12)14-8)16(5-13-7)6-3-1-2-4-6/h1-2,5-6H,3-4H2,(H2,12,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+5	n/a	n/a	n/a	n/a	7.2	30
Institut Curie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				Bioorg Med Chem 7: 1281-93 (1999) Article DOI: 10.1016/S0968-0896(99)00064-4 BindingDB Entry DOI: 10.7270/Q23776X6
					More data for this Ligand-Target Pair