BDBM75086 1-(1-Amino-5-methyl-6,7,8,9-tetrahydro-thieno[2,3-c]isoquinolin-2-yl)-ethanone::1-(1-amino-5-methyl-6,7,8,9-tetrahydrothien[2,3-c]isoquinolin-2-yl)ethanone::1-(1-amino-5-methyl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinolin-2-yl)ethanone::1-(1-azanyl-5-methyl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinolin-2-yl)ethanone::MLS000767803::SMR000430132::cid_931268

SMILES: CC(=O)c1sc2nc(C)c3CCCCc3c2c1N

InChI Key: InChIKey=RUHQGRNZZQGBIG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM75086 (1-(1-Amino-5-methyl-6,7,8,9-tetrahydro-thieno[2,3-...) Show SMILES CC(=O)c1sc2nc(C)c3CCCCc3c2c1N Show InChI InChI=1S/C14H16N2OS/c1-7-9-5-3-4-6-10(9)11-12(15)13(8(2)17)18-14(11)16-7/h3-6,15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair