BDBM75105 4-(3-bromo-4,5-dimethoxy-phenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl ester::4-(3-bromo-4,5-dimethoxyphenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylic acid dimethyl ester::MLS000910937::SMR000109872::cid_2172338::dimethyl 4-(3-bromanyl-4,5-dimethoxy-phenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylate::dimethyl 4-(3-bromo-4,5-dimethoxyphenyl)-1-(2-methoxyethyl)-4H-pyridine-3,5-dicarboxylate

SMILES: COCCN1C=C(C(C(=C1)C(=O)OC)c1cc(Br)c(OC)c(OC)c1)C(=O)OC

InChI Key: InChIKey=QMDDTWGQSBYSAK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 75105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b (Homo sapiens (Human))	BDBM75105 (4-(3-bromo-4,5-dimethoxy-phenyl)-1-(2-methoxyethyl...) Show SMILES COCCN1C=C(C(C(=C1)C(=O)OC)c1cc(Br)c(OC)c(OC)c1)C(=O)OC |c:5,8| Show InChI InChI=1S/C20H24BrNO7/c1-25-7-6-22-10-13(19(23)28-4)17(14(11-22)20(24)29-5)12-8-15(21)18(27-3)16(9-12)26-2/h8-11,17H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.05E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q280513R
					More data for this Ligand-Target Pair