BDBM76329 2-methyl-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)-2-propenamide::2-methyl-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)prop-2-enamide::2-methyl-N-[5-(2-thienyl)-1,3,4-thiadiazol-2-yl]acrylamide::MLS000683806::SMR000272413::cid_898899

SMILES: CC(=C)C(=O)Nc1nnc(s1)-c1cccs1

InChI Key: InChIKey=JBOGIULJDVDVQV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 76329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-1 (Homo sapiens (Human))	BDBM76329 (2-methyl-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)...) Show SMILES CC(=C)C(=O)Nc1nnc(s1)-c1cccs1 Show InChI InChI=1S/C10H9N3OS2/c1-6(2)8(14)11-10-13-12-9(16-10)7-4-3-5-15-7/h3-5H,1H2,2H3,(H,11,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TD9VTQ
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 1 isoform 1 (Homo sapiens (Human))	BDBM76329 (2-methyl-N-(5-thiophen-2-yl-1,3,4-thiadiazol-2-yl)...) Show SMILES CC(=C)C(=O)Nc1nnc(s1)-c1cccs1 Show InChI InChI=1S/C10H9N3OS2/c1-6(2)8(14)11-10-13-12-9(16-10)7-4-3-5-15-7/h3-5H,1H2,2H3,(H,11,13,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q22Z140X
					More data for this Ligand-Target Pair