BDBM7803 1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione::Maleimide-Related Compound 2

SMILES: CN1C(=O)C=CC1=O

InChI Key: InChIKey=SEEYREPSKCQBBF-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 3 PDB IDs contain this monomer as substructures. 5 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7803   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM7803 (1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione | Maleim...) Show SMILES CN1C(=O)C=CC1=O |c:4| Show InChI InChI=1S/C5H5NO2/c1-6-4(7)2-3-5(6)8/h2-3H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Louvain Drug Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]2-OG from human MGL by liquid scintillation counting				J Med Chem 52: 7410-20 (2009) Article DOI: 10.1021/jm900461w BindingDB Entry DOI: 10.7270/Q2TM7B59
					More data for this Ligand-Target Pair
Glycogen Synthase Kinase-3, beta (Oryctolagus cuniculus (rabbit))	BDBM7803 (1-methyl-2,5-dihydro-1H-pyrrole-2,5-dione | Maleim...) Show SMILES CN1C(=O)C=CC1=O |c:4| Show InChI InChI=1S/C5H5NO2/c1-6-4(7)2-3-5(6)8/h2-3H,1H3	GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	7.5	37
Instituto de Quimica Medica (CSIC)					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 48: 7103-12 (2005) Article DOI: 10.1021/jm040895g BindingDB Entry DOI: 10.7270/Q2J964MP
					More data for this Ligand-Target Pair