BDBM7847 US8822458, 15

SMILES: Fc1cc(ccc1N1CCS(=O)(=O)CC1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O

InChI Key: InChIKey=AHQZLOQYCWPLBA-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM7847 (US8822458, 15) Show SMILES Fc1cc(ccc1N1CCS(=O)(=O)CC1)N1C[C@H](CNC(=O)c2ccc(Cl)s2)OC1=O |r| Show InChI InChI=1S/C19H19ClFN3O5S2/c20-17-4-3-16(30-17)18(25)22-10-13-11-24(19(26)29-13)12-1-2-15(14(21)9-12)23-5-7-31(27,28)8-6-23/h1-4,9,13H,5-8,10-11H2,(H,22,25)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	25
Bayer Intellectual Property GmbH US Patent					Assay Description The enzymatic activity of human factor Xa (FXa) was measured using the conversion of a chromogenic substrate specific for FXa. Factor Xa cleaves p-ni...				US Patent US8822458 (2014) BindingDB Entry DOI: 10.7270/Q2VH5MJ2
					More data for this Ligand-Target Pair