BDBM7848 2-Ethyl-4-(4-nitrophenyl)-1,2,4-thiadiazolidine-3,5-dione::Thiadiazolidinone (TDZD) deriv. 55

SMILES: CCn1sc(=O)n(-c2ccc(cc2)N(=O)=O)c1=O

InChI Key: InChIKey=NDJXFBOMEIBNON-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7848   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen Synthase Kinase-3, beta (Oryctolagus cuniculus (rabbit))	BDBM7848 (2-Ethyl-4-(4-nitrophenyl)-1,2,4-thiadiazolidine-3,...) Show SMILES CCn1sc(=O)n(-c2ccc(cc2)N(=O)=O)c1=O Show InChI InChI=1S/C10H9N3O4S/c1-2-11-9(14)12(10(15)18-11)7-3-5-8(6-4-7)13(16)17/h3-6H,2H2,1H3	GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	37
Instituto de Quimica Medica (CSIC)					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 48: 7103-12 (2005) Article DOI: 10.1021/jm040895g BindingDB Entry DOI: 10.7270/Q2J964MP
					More data for this Ligand-Target Pair