BDBM79219 6-cyclopropyl-1-isopropyl-N-(4-sulfamoylphenyl)pyrazolo[3,4-b]pyridine-4-carboxamide::6-cyclopropyl-1-propan-2-yl-N-(4-sulfamoylphenyl)-4-pyrazolo[3,4-b]pyridinecarboxamide::6-cyclopropyl-1-propan-2-yl-N-(4-sulfamoylphenyl)pyrazolo[3,4-b]pyridine-4-carboxamide::MLS002171224::SMR001251521::cid_9268118

SMILES: CC(C)n1ncc2c(cc(nc12)C1CC1)C(=O)Nc1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=PCGVSZRRVBOKJA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 79219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ubiquitin-conjugating enzyme E2 N (Homo sapiens (Human))	BDBM79219 (6-cyclopropyl-1-isopropyl-N-(4-sulfamoylphenyl)pyr...) Show SMILES CC(C)n1ncc2c(cc(nc12)C1CC1)C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H21N5O3S/c1-11(2)24-18-16(10-21-24)15(9-17(23-18)12-3-4-12)19(25)22-13-5-7-14(8-6-13)28(20,26)27/h5-12H,3-4H2,1-2H3,(H,22,25)(H2,20,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2X34VX0
					More data for this Ligand-Target Pair
26S Proteasome regulatory subunit Rpn11 (Rpn11) (Homo sapiens (Human))	BDBM79219 (6-cyclopropyl-1-isopropyl-N-(4-sulfamoylphenyl)pyr...) Show SMILES CC(C)n1ncc2c(cc(nc12)C1CC1)C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H21N5O3S/c1-11(2)24-18-16(10-21-24)15(9-17(23-18)12-3-4-12)19(25)22-13-5-7-14(8-6-13)28(20,26)27/h5-12H,3-4H2,1-2H3,(H,22,25)(H2,20,26,27)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2PC30Z9
					More data for this Ligand-Target Pair
Thrombin (Bos taurus (Bovine))	BDBM79219 (6-cyclopropyl-1-isopropyl-N-(4-sulfamoylphenyl)pyr...) Show SMILES CC(C)n1ncc2c(cc(nc12)C1CC1)C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H21N5O3S/c1-11(2)24-18-16(10-21-24)15(9-17(23-18)12-3-4-12)19(25)22-13-5-7-14(8-6-13)28(20,26)27/h5-12H,3-4H2,1-2H3,(H,22,25)(H2,20,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	7.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford Burnham Medical Research Institute (SBMRI, La Jolla, CA...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2JM286J
					More data for this Ligand-Target Pair