BDBM81020 (3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methanethione::(3,4-dichlorophenyl)-(4-ethylpiperazin-1-yl)methanethione::(3,4-dichlorophenyl)-(4-ethylpiperazino)methanethione::1-[(3,4-dichlorophenyl)carbonothioyl]-4-ethylpiperazine::MLS000594177::SMR000143195::cid_848275

SMILES: CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=YSWVIGJDOZEAPY-UHFFFAOYSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 81020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucose 6-phosphate dehydrogenase (G6PD) (Homo sapiens (Human))	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V12389
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.81E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2ZS2TZG
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q27H1H3W
					More data for this Ligand-Target Pair
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium falciparum 3D7)	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q23T9FQ1
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2FQ9V6B
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase (VHR) (Homo sapiens (Human))	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2959G44
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	843	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2T43RPN
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2KH0KWR
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 5 isoform a (Homo sapiens (Human))	BDBM81020 ((3,4-dichlorophenyl)-(4-ethyl-1-piperazinyl)methan...) Show SMILES CCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H16Cl2N2S/c1-2-16-5-7-17(8-6-16)13(18)10-3-4-11(14)12(15)9-10/h3-4,9H,2,5-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2DV1HGT
					More data for this Ligand-Target Pair