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BDBM81354 Fumarranol Analog, 9

SMILES: [#6]-[#8][C@@]12[#6]([C@@]3([#6])[#8]-[#6@@H]3-[#6]\[#6]=[#6](\[#6])-[#6])[C@]1([#6]-[#8])[#6]\[#6](=[#6]/c1ccco1)-[#6]2=O

InChI Key: InChIKey=WBDKQISNJNJFMX-LXLQUSSSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81354   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Methionine aminopeptidase (MetAP2)


(Plasmodium falciparum)		BDBM81354
PNG
(Fumarranol Analog, 9)
Show SMILES [#6]-[#8][C@@]12[#6]([C@@]3([#6])[#8]-[#6@@H]3-[#6]\[#6]=[#6](\[#6])-[#6])[C@]1([#6]-[#8])[#6]\[#6](=[#6]/c1ccco1)-[#6]2=O |r|
Show InChI InChI=1S/C21H26O5/c1-13(2)7-8-16-19(3,26-16)18-20(12-22)11-14(10-15-6-5-9-25-15)17(23)21(18,20)24-4/h5-7,9-10,16,18,22H,8,11-12H2,1-4H3/b14-10+/t16-,18?,19+,20-,21+/m1/s1
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Johns Hopkins School of Medicine



Assay Description
Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).

Chem Biol 16: 193-202 (2009)


Article DOI: 10.1016/j.chembiol.2009.01.006
BindingDB Entry DOI: 10.7270/Q2WS8RQ5
More data for this
Ligand-Target Pair