Found 4 hits for monomerid = 81464 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H1 receptor
(RAT) | BDBM81464
(2-[(4-chlorophenyl)-(2-pyridyl)methoxy]ethyl-dimet...)Show InChI InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3 | KEGG
UniProtKB/SwissProt
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DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 75: 6290-4 (1978)
Article DOI: 10.1073/pnas.75.12.6290 BindingDB Entry DOI: 10.7270/Q2FN14P6 |
More data for this Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1S
(Rattus norvegicus) | BDBM81464
(2-[(4-chlorophenyl)-(2-pyridyl)methoxy]ethyl-dimet...)Show InChI InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Perugia
Curated by ChEMBL
| Assay Description Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes |
J Med Chem 51: 5552-65 (2008)
Article DOI: 10.1021/jm800151n BindingDB Entry DOI: 10.7270/Q24T6N5H |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM81464
(2-[(4-chlorophenyl)-(2-pyridyl)methoxy]ethyl-dimet...)Show InChI InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-... |
Drug Metab Dispos 40: 2332-41 (2012)
Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M |
More data for this Ligand-Target Pair | |
Chain A, Crystal Structure Of The B1b2 Domains From Human Neuropilin- 1
(Homo sapiens (Human)) | BDBM81464
(2-[(4-chlorophenyl)-(2-pyridyl)methoxy]ethyl-dimet...)Show InChI InChI=1S/C16H19ClN2O/c1-19(2)11-12-20-16(15-5-3-4-10-18-15)13-6-8-14(17)9-7-13/h3-10,16H,11-12H2,1-2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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DrugBank KEGG PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | >9.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| |
PubChem Bioassay (2012)
BindingDB Entry DOI: 10.7270/Q2HM5725 |
More data for this Ligand-Target Pair | |