BDBM81515 VEA-499
SMILES: C[C@H](O)C(NC(=O)[C@H](CCC(N)=O)NC(=O)Cc1ccc(O)c(c1)N(=O)=O)C(=O)NCC(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
InChI Key: InChIKey=NEBHTMJIPDLGNE-QQFJOJBBSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sentrin-specific protease 1 (SENP1) (Homo sapiens (Human)) | BDBM81515 (VEA-499) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Stanford University | Assay Description The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ... | Chem Biol 18: 722-32 (2011) Article DOI: 10.1016/j.chembiol.2011.05.008 BindingDB Entry DOI: 10.7270/Q2542M2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sentrin-specific protease 7 (SENP7) (Homo sapiens (Human)) | BDBM81515 (VEA-499) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Stanford University | Assay Description The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ... | Chem Biol 18: 722-32 (2011) Article DOI: 10.1016/j.chembiol.2011.05.008 BindingDB Entry DOI: 10.7270/Q2542M2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
SUMO-1-specific protease (Homo sapiens (Human)) | BDBM81515 (VEA-499) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Stanford University | Assay Description The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ... | Chem Biol 18: 722-32 (2011) Article DOI: 10.1016/j.chembiol.2011.05.008 BindingDB Entry DOI: 10.7270/Q2542M2N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sentrin-specific protease 2 (SENP2) (Homo sapiens (Human)) | BDBM81515 (VEA-499) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Stanford University | Assay Description The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ... | Chem Biol 18: 722-32 (2011) Article DOI: 10.1016/j.chembiol.2011.05.008 BindingDB Entry DOI: 10.7270/Q2542M2N | |||||||||||
More data for this Ligand-Target Pair |