BDBM81681 P1 Phenyl Ring, 22

SMILES: NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2CCCN2C(=O)Nc2ccc(Br)cc2)c(F)c1

InChI Key: InChIKey=HICSFOWYIPJAEW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 81681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM81681 (P1 Phenyl Ring, 22) Show SMILES NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2CCCN2C(=O)Nc2ccc(Br)cc2)c(F)c1 Show InChI InChI=1S/C24H22BrFN4O4S/c25-16-8-10-17(11-9-16)28-24(32)30-13-3-5-21(30)23(31)29-20-12-7-15(14-19(20)26)18-4-1-2-6-22(18)35(27,33)34/h1-2,4,6-12,14,21H,3,5,13H2,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development,					Assay Description FXa inhibition were determined by using an inhibition assay.				Chem Biol Drug Des 69: 444-50 (2007) Article DOI: 10.1111/j.1747-0285.2007.00520.x BindingDB Entry DOI: 10.7270/Q2PZ5799
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