BindingDB PrimarySearch

BDBM82032 1,3-Dipropyl-3,7-dihydro-purine-2,6-dione::1,3-Dipropylxanthine::CAS_169317::CHEMBL157655::CPX::NSC_169317

SMILES: CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O

InChI Key: InChIKey=MJVIGUCNSRXAFO-UHFFFAOYSA-N

Data: 46 KI 1 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 48 hits for monomerid = 82032
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ADORA1 (Chick)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 81-6 (2001) Article DOI: 10.1007/s002100000340 BindingDB Entry DOI: 10.7270/Q25Q4TNC
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by PDSP K_i Database									Mol Pharmacol 56: 705-13 (1999) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2M9077B
University of Virginia Curated by PDSP K_i Database					More data for this Ligand-Target Pair
ADORA3 (Chick)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	Reactome pathway GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	53.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 81-6 (2001) Article DOI: 10.1007/s002100000340 BindingDB Entry DOI: 10.7270/Q25Q4TNC
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by PDSP K_i Database									Mol Pharmacol 56: 705-13 (1999) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2M9077B
University of Virginia Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by PDSP K_i Database									Mol Pharmacol 56: 705-13 (1999) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2M9077B
University of Virginia Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Affinity against adenosine A1 receptor in the brain membranes by the displacement of [3H]-CPX.				J Med Chem 35: 4039-44 (1992) BindingDB Entry DOI: 10.7270/Q2CF9P23
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor of cerebral cortex using [3H]-CPX as a radioligand				J Med Chem 36: 1380-6 (1993) BindingDB Entry DOI: 10.7270/Q23B5Z65
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Inhibition of binding of 1 nM [3H]N-6-(phenylisopropyl)adenosine to adenosine A1 receptor in rat cortical membranes				J Med Chem 32: 1873-9 (1989) BindingDB Entry DOI: 10.7270/Q2708213
NIDDK Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity against Adenosine A1 receptor using N6-[3H]-cyclohexyladenosinene in rat whole brain membranes				J Med Chem 35: 924-30 (1992) BindingDB Entry DOI: 10.7270/Q2NS0VJZ
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by PDSP K_i Database									Mol Pharmacol 29: 331-46 (1986) BindingDB Entry DOI: 10.7270/Q2MK6BDV
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of N6-[3H]-cyclohexyladenosine binding to adenosine A1 receptor from whole brain membranes				J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Binding affinity against Adenosine A1 receptor in rat brain membrane, using [3H]-N6-cyclohexyladenosine as the radioligand				J Med Chem 32: 2247-54 (1989) BindingDB Entry DOI: 10.7270/Q2H70DTD
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	509	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by PDSP K_i Database									Mol Pharmacol 56: 705-13 (1999) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2M9077B
University of Virginia Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibition of adenosine stimulated accumulation of cyclic AMP at Adenosine A2 receptor of VA13 fibroblasts of rat				J Med Chem 31: 2034-9 (1988) BindingDB Entry DOI: 10.7270/Q2988614
Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universität Tübingen Curated by ChEMBL					Assay Description Binding affinity to A1 adenosine receptor from rat cortical membrane in presence of [3H]-R-(phenylisopropyl)-adenosine				J Med Chem 37: 1526-34 (1994) BindingDB Entry DOI: 10.7270/Q28P5ZJN
Eberhard-Karls-Universität Tübingen Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merrell Dow Research Institute Curated by ChEMBL					Assay Description Binding of 1 nM [3H]-CHA to Adenosine A1 receptor of rat cerebral cortical membranes				J Med Chem 31: 2034-9 (1988) BindingDB Entry DOI: 10.7270/Q2988614
Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Binding affinity for adenosine A1 receptor from rat brain membranes using [3H]-PIA as radioligand				J Med Chem 36: 2639-44 (1993) BindingDB Entry DOI: 10.7270/Q2S75FDT
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmazeutische Chemie Curated by ChEMBL					Assay Description Binding affinity at Adenosine A1 receptor in rat brain cortical membrane using [3H]-N6-R-phenylisopropyladenosine (R-PIA) as radioligand				J Med Chem 36: 3341-9 (1993) BindingDB Entry DOI: 10.7270/Q26Q1W9W
Pharmazeutische Chemie Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit binding of 1 nM [3H]-cyclohexyladenosine to adenosine A1 receptor in rat cerebral cortical membranes				J Med Chem 29: 1305-8 (1987) BindingDB Entry DOI: 10.7270/Q23777QX
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonism of binding of 1 nM [3H]cyclohexyladenosine to adenosine A1 receptors on rat cortical membranes				J Med Chem 28: 487-92 (1985) BindingDB Entry DOI: 10.7270/Q2RV0P8X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Inhibition of 1 nM [3H]- N6-(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat cerebral cortical membranes				J Med Chem 32: 1231-7 (1989) BindingDB Entry DOI: 10.7270/Q2PZ57T1
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity against Adenosine A1 receptor using N6-[3H]cyclohexyladenosine in guinea pig membranes				J Med Chem 35: 924-30 (1992) BindingDB Entry DOI: 10.7270/Q2NS0VJZ
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes & Digestive & Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at human Adenosine A2B receptor expressed in HEK-293 cells, using [125I]-ABOPX as radioligand				J Med Chem 45: 2131-8 (2002) BindingDB Entry DOI: 10.7270/Q2V1243G
					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]-cyclohexyladenosine binding to guinea pig forebrain membranes Adenosine A1 receptor				J Med Chem 34: 466-9 (1991) BindingDB Entry DOI: 10.7270/Q2154G0Z
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor from guinea pig forebrain membranes, using N6-[3H]-cyclohexyladenosine as radioligand.				J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A1 receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity against Adenosine A1 receptor using N6-[3H]cyclohexyladenosine in guinea pig membranes				J Med Chem 35: 924-30 (1992) BindingDB Entry DOI: 10.7270/Q2NS0VJZ
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membrane				J Med Chem 32: 1231-7 (1989) BindingDB Entry DOI: 10.7270/Q2PZ57T1
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of [3H]5'-(N-ethylcarbamoyl)-adenosine binding to Adenosine A2 receptor in rat striatal membranes in the presence of 50 nM cyclopentyladen...				J Med Chem 34: 466-9 (1991) BindingDB Entry DOI: 10.7270/Q2154G0Z
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of N6-[3H]-cyclohexyladenosine binding to adenosine A1 receptor from whole brain membranes				J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Binding affinity against adenosine A2 receptor of striatal membrane using [3H]CGS-21680 as a radioligand				J Med Chem 36: 1380-6 (1993) BindingDB Entry DOI: 10.7270/Q23B5Z65
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity against Adenosine A2 receptor using N-[3H]-ethyladenosin-5''-uronamide in rat striatal membranes				J Med Chem 35: 924-30 (1992) BindingDB Entry DOI: 10.7270/Q2NS0VJZ
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Binding affinity for adenosine A2A receptor from rat brain membranes using [3H]-CGS-21,680				J Med Chem 36: 2639-44 (1993) BindingDB Entry DOI: 10.7270/Q2S75FDT
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2a receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonism of cyclic [3H]AMP accumulation in guinea pig cerebral cortical slices (elicited by 15 uM 2-chloroadenosine at adenosine A2 receptor)				J Med Chem 28: 487-92 (1985) BindingDB Entry DOI: 10.7270/Q2RV0P8X
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merrell Dow Research Institute Curated by ChEMBL					Assay Description Inhibition of 2-CADO-stimulated adenylate cyclase at Adenosine A2 receptor in guinea pig cerebral cortical slices				J Med Chem 31: 2034-9 (1988) BindingDB Entry DOI: 10.7270/Q2988614
Merrell Dow Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2a receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to antagonise cyclic [3H]-AMP accumulation in [3H]-adenine-labeled guinea pig cerebral cortical slices.				J Med Chem 29: 1305-8 (1987) BindingDB Entry DOI: 10.7270/Q23777QX
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2a receptor (GUINEA PIG)	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Affinity against adenosine A2 receptor in the brain membranes measured by the displacement of [3H]-CPX				J Med Chem 35: 4039-44 (1992) BindingDB Entry DOI: 10.7270/Q2CF9P23
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Binding affinity against Adenosine A2 receptor using N-[3H]-ethyl adenosine-5-uronamide in rat striatal membranes				J Med Chem 35: 924-30 (1992) BindingDB Entry DOI: 10.7270/Q2NS0VJZ
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDDK Curated by ChEMBL					Assay Description Inhibition of binding of [3H]5'-(N-ethylcarbamoyl)-adenosine to adenosine A2 receptor in rat striatal membranes				J Med Chem 32: 1873-9 (1989) BindingDB Entry DOI: 10.7270/Q2708213
NIDDK Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by PDSP K_i Database									Mol Pharmacol 29: 331-46 (1986) BindingDB Entry DOI: 10.7270/Q2MK6BDV
					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					Assay Description Inhibition of N-[3H]-ethyladenosin-5''-uronamide binding to adenosine A2 receptor from rat striatal membranes				J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of South Florida Curated by ChEMBL					Assay Description Binding affinity against Adenosine A2 receptor in rat brain membrane, using [3H]-NECA as the radioligand.				J Med Chem 32: 2247-54 (1989) BindingDB Entry DOI: 10.7270/Q2H70DTD
University of South Florida Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Inhibition of the stimulation by 5'-(N-ethylcarbamoyl) adenosine of adenyl cyclase via Adenosine A2 receptor in rat PC12 membranes				J Med Chem 32: 1231-7 (1989) BindingDB Entry DOI: 10.7270/Q2PZ57T1
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmazeutische Chemie Curated by ChEMBL					Assay Description Binding affinity against Adenosine A2 receptor in rat striatal membranes using [3H]5'-(N-ethylcarboxamido)-adenosine (NECA) as the ligand				J Med Chem 36: 3341-9 (1993) BindingDB Entry DOI: 10.7270/Q26Q1W9W
Pharmazeutische Chemie Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine A2 receptor (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Inhibition of 1 nM [3H]- N6 -(phenylisopropyl) adenosine binding to Adenosine A1 receptor in rat fat cell membrane				J Med Chem 32: 1231-7 (1989) BindingDB Entry DOI: 10.7270/Q2PZ57T1
National Institutes of Health Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.61E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of cyclic AMP-phosphodiesterase ( PDE) in the supernatant of tracheal muscle homogenate				J Med Chem 36: 1380-6 (1993) BindingDB Entry DOI: 10.7270/Q23B5Z65
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.61E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of c-AMP phosphodiesterase activity in guinea pig tracheal muscle				J Med Chem 35: 4039-44 (1992) BindingDB Entry DOI: 10.7270/Q2CF9P23
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Relexant activity on the spontaneous tone of isolated guinea pig tracheal ring chains.				J Med Chem 35: 4039-44 (1992) BindingDB Entry DOI: 10.7270/Q2CF9P23
Hokuriku University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM82032 (1,3-Dipropyl-3,7-dihydro-purine-2,6-dione \| 1,3-Di...) Show SMILES CCCn1c2nc[nH]c2c(=O)n(CCC)c1=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonism of adenosine A1 receptor assessed from the ability to inhibit binding of [3H]-cyclohexyladenosine to rat cerebral cortical membranes				J Med Chem 27: 1364-7 (1984) BindingDB Entry DOI: 10.7270/Q2K35SP9
TBA Curated by ChEMBL					More data for this Ligand-Target Pair