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BDBM82135 5-Substituted derivative, 5

SMILES: Clc1ccc2N(CCN3CCOCC3)C(=O)\C(=N/c3cccc4ccccc34)c2c1

InChI Key: InChIKey=ALQISWGNLKTFQH-RWEWTDSWSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 82135   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))		BDBM82135
PNG
(5-Substituted derivative, 5)
Show SMILES Clc1ccc2N(CCN3CCOCC3)C(=O)\C(=N/c3cccc4ccccc34)c2c1
Show InChI InChI=1S/C24H22ClN3O2/c25-18-8-9-22-20(16-18)23(24(29)28(22)11-10-27-12-14-30-15-13-27)26-21-7-3-5-17-4-1-2-6-19(17)21/h1-9,16H,10-15H2/b26-23-
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Article
PubMed
 8.40 -11.0n/an/an/an/an/a7.425



Università di Napoli Federico II



Assay Description
CB1 competitive assay were performed in rat cerebellar membranes using [3H]WIN 55212-2 from Perkin-Elmer as a radioligand.

Chem Biol Drug Des 75: 106-14 (2010)


Article DOI: 10.1111/j.1747-0285.2009.00910.x
BindingDB Entry DOI: 10.7270/Q2GM85SK
More data for this
Ligand-Target Pair