BDBM82248 CAS_73445-63-3::SCH 23388 (S-enantiomer)

SMILES: CN1CCc2cc(Cl)c(O)cc2[C@@H](C1)c1ccccc1

InChI Key: InChIKey=GOTMKOSCLKVOGG-HNNXBMFYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 82248   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM82248 (CAS_73445-63-3 | SCH 23388 (S-enantiomer)) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Northeastern University Curated by ChEMBL					Assay Description Ability to partially antagonise [3H]-SCH- 23388 binding to the Dopamine receptor D2				J Med Chem 31: 2069-71 (1988) BindingDB Entry DOI: 10.7270/Q2B56K9S
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM82248 (CAS_73445-63-3 | SCH 23388 (S-enantiomer)) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	192	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by PDSP Ki Database									Life Sci 35: 1885-93 (1984) Article DOI: 10.1016/0024-3205(84)90540-x BindingDB Entry DOI: 10.7270/Q2JD4V9M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM82248 (CAS_73445-63-3 | SCH 23388 (S-enantiomer)) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	192	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Lund Curated by ChEMBL					Assay Description Compound was tested for the displacement of [3H]-SCH- 23390 from dopamine receptor D1				J Med Chem 35: 502-7 (1992) BindingDB Entry DOI: 10.7270/Q2TH8N95
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM82248 (CAS_73445-63-3 | SCH 23388 (S-enantiomer)) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	988	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Corporation Curated by PDSP Ki Database									Life Sci 35: 1885-93 (1984) Article DOI: 10.1016/0024-3205(84)90540-x BindingDB Entry DOI: 10.7270/Q2JD4V9M
					More data for this Ligand-Target Pair