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SMILES: Cc1cn(CN2CCN(CCc3ccccc3)CC2)c2ccccc12

InChI Key: InChIKey=AEYSRYMQRKDECJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 82351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM82351 (1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...) Show SMILES Cc1cn(CN2CCN(CCc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C22H27N3/c1-19-17-25(22-10-6-5-9-21(19)22)18-24-15-13-23(14-16-24)12-11-20-7-3-2-4-8-20/h2-10,17H,11-16,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mazandaran University of Medical Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting method				Eur J Med Chem 150: 9-29 (2018) Article DOI: 10.1016/j.ejmech.2018.02.065 BindingDB Entry DOI: 10.7270/Q2X92DXX
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM82351 (1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...) Show SMILES Cc1cn(CN2CCN(CCc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C22H27N3/c1-19-17-25(22-10-6-5-9-21(19)22)18-24-15-13-23(14-16-24)12-11-20-7-3-2-4-8-20/h2-10,17H,11-16,18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14.2	-11.1	n/a	n/a	n/a	n/a	n/a	7.4	37
Yeditepe University					Assay Description The test was performed with the radioligand [3H]-(+)-pentazocine (42.5 Ci/mmol) from Perkin Elmer.				Chem Biol Drug Des 78: 869-75 (2011) Article DOI: 10.1111/j.1747-0285.2011.01215.x BindingDB Entry DOI: 10.7270/Q2513WQT
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM82351 (1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...) Show SMILES Cc1cn(CN2CCN(CCc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C22H27N3/c1-19-17-25(22-10-6-5-9-21(19)22)18-24-15-13-23(14-16-24)12-11-20-7-3-2-4-8-20/h2-10,17H,11-16,18H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mazandaran University of Medical Sciences Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting method				Eur J Med Chem 150: 9-29 (2018) Article DOI: 10.1016/j.ejmech.2018.02.065 BindingDB Entry DOI: 10.7270/Q2X92DXX
					More data for this Ligand-Target Pair