BindingDB PrimarySearch

BDBM82422 CAS_109872-41-5::NSC_3035240::RENZAPRIDE

SMILES: COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCCC1C2

InChI Key: InChIKey=GZSKEXSLDPEFPT-UHFFFAOYSA-N

Data: 26 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 82422
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
HTR4 (RAT)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Eur J Pharmacol 304: 231-5 (1996) Article DOI: 10.1016/0014-2999(96)00122-7 BindingDB Entry DOI: 10.7270/Q2CN72FW
					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	97.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									FEBS Lett 398: 19-25 (1996) Article DOI: 10.1016/s0014-5793(96)01132-5 BindingDB Entry DOI: 10.7270/Q228065Q
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	97.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	97.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd. Curated by PDSP K_i Database									Br J Pharmacol 109: 618-24 (1993) Article DOI: 10.1111/j.1476-5381.1993.tb13617.x BindingDB Entry DOI: 10.7270/Q2CZ35PV
Glaxo Group Research Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 (1994) Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (GUINEA PIG)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd. Curated by PDSP K_i Database									Br J Pharmacol 109: 618-24 (1993) Article DOI: 10.1111/j.1476-5381.1993.tb13617.x BindingDB Entry DOI: 10.7270/Q2CZ35PV
Glaxo Group Research Ltd. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									FEBS Lett 398: 19-25 (1996) Article DOI: 10.1016/s0014-5793(96)01132-5 BindingDB Entry DOI: 10.7270/Q228065Q
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	173	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Paris-Sud Curated by PDSP K_i Database									J Neurochem 70: 2252-61 (1998) Article DOI: 10.1046/j.1471-4159.1998.70062252.x BindingDB Entry DOI: 10.7270/Q2Z036PW
Université de Paris-Sud Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	174	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
University of Oslo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	243	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									EMBO J 14: 2806-15 (1995) BindingDB Entry DOI: 10.7270/Q2BK19VW
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	243	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Eur J Pharmacol 304: 231-5 (1996) Article DOI: 10.1016/0014-2999(96)00122-7 BindingDB Entry DOI: 10.7270/Q2CN72FW
					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP K_i Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
CNRS UPR 9023 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR4 (RAT)	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 671-9 (1997) Article DOI: 10.1016/s0028-3908(97)00039-7 BindingDB Entry DOI: 10.7270/Q2RN36D0
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
University of Oslo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	635	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Paris-Sud Curated by PDSP K_i Database									J Neurochem 70: 2252-61 (1998) Article DOI: 10.1046/j.1471-4159.1998.70062252.x BindingDB Entry DOI: 10.7270/Q2Z036PW
Université de Paris-Sud Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	636	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Paris-Sud Curated by PDSP K_i Database									J Neurochem 70: 2252-61 (1998) Article DOI: 10.1046/j.1471-4159.1998.70062252.x BindingDB Entry DOI: 10.7270/Q2Z036PW
Université de Paris-Sud Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP K_i Database									J Biol Chem 268: 18200-4 (1993) BindingDB Entry DOI: 10.7270/Q2V1239R
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Neurological Disorders and Stroke Curated by PDSP K_i Database									J Biol Chem 268: 18200-4 (1993) BindingDB Entry DOI: 10.7270/Q2V1239R
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM82422 (CAS_109872-41-5 \| NSC_3035240 \| RENZAPRIDE) Show SMILES Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Paris-Sud Curated by PDSP K_i Database									J Neurochem 70: 2252-61 (1998) Article DOI: 10.1046/j.1471-4159.1998.70062252.x BindingDB Entry DOI: 10.7270/Q2Z036PW
Université de Paris-Sud Curated by PDSP K_i Database					More data for this Ligand-Target Pair