Found 9 hits for monomerid = 82498 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(GUINEA PIG) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 4.26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 270: 665-74 (1994)
BindingDB Entry DOI: 10.7270/Q2RN36CJ |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 6.16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 270: 665-74 (1994)
BindingDB Entry DOI: 10.7270/Q2RN36CJ |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(GUINEA PIG) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 270: 665-74 (1994)
BindingDB Entry DOI: 10.7270/Q2RN36CJ |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 7.41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 270: 665-74 (1994)
BindingDB Entry DOI: 10.7270/Q2RN36CJ |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 270: 665-74 (1994)
BindingDB Entry DOI: 10.7270/Q2RN36CJ |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(GUINEA PIG) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| 34.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 270: 665-74 (1994)
BindingDB Entry DOI: 10.7270/Q2RN36CJ |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(GUINEA PIG) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description Inhibitory activity against Beta-2 adrenergic receptor in guinea pig trachea after treatment with the compound |
J Med Chem 35: 466-79 (1992)
BindingDB Entry DOI: 10.7270/Q27D2WF8 |
More data for this Ligand-Target Pair | |
Prostanoid TP receptor
(Homo sapiens (Human)) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.58E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description Inhibitory activity against U-46,619-induced responses in human platelet aggregation (Thromboxane A2 alpha receptor) |
J Med Chem 35: 466-79 (1992)
BindingDB Entry DOI: 10.7270/Q27D2WF8 |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(GUINEA PIG) | BDBM82498
(TMQ, 5,8-Difluoro)Show SMILES COc1cc(CC2NCCc3c(F)c(O)c(O)c(F)c23)cc(OC)c1OC Show InChI InChI=1S/C19H21F2NO5/c1-25-12-7-9(8-13(26-2)19(12)27-3)6-11-14-10(4-5-22-11)15(20)17(23)18(24)16(14)21/h7-8,11,22-24H,4-6H2,1-3H3 | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
Ohio State University
Curated by ChEMBL
| Assay Description Inhibitory activity against Beta-1 adrenergic receptor in guinea pig atria after treatment with the compound |
J Med Chem 35: 466-79 (1992)
BindingDB Entry DOI: 10.7270/Q27D2WF8 |
More data for this Ligand-Target Pair | |