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SMILES: OCC(CN1C(=O)c2ccc(cc2C1=O)C(F)(F)F)N1CCC(CC1)c1noc2cc(F)ccc12

InChI Key: InChIKey=YPIYNYPMMRCRCR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 84455   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM84455
PNG
(Isoindoline, 22)
Show SMILES OCC(CN1C(=O)c2ccc(cc2C1=O)C(F)(F)F)N1CCC(CC1)c1noc2cc(F)ccc12
Show InChI InChI=1S/C24H21F4N3O4/c25-15-2-4-18-20(10-15)35-29-21(18)13-5-7-30(8-6-13)16(12-32)11-31-22(33)17-3-1-14(24(26,27)28)9-19(17)23(31)34/h1-4,9-10,13,16,32H,5-8,11-12H2
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Article
PubMed
 727n/an/an/an/an/an/an/an/a



Aventis Pharmaceuticals



Assay Description
Dopamine D4.2 and D2S receptor binding was performed at NPS Allexlix Corp.

Chembiochem 3: 999-1009 (2002)


Article DOI: 10.1002/1439-7633(20021004)3:10
BindingDB Entry DOI: 10.7270/Q27D2SP5
More data for this
Ligand-Target Pair