BDBM84525 Sulindac analogue, 22

SMILES: CC1=C(CC(O)=O)c2cc(I)ccc2\C1=C/c1cccc(OCc2ccccc2)c1

InChI Key: InChIKey=IFCUQPZYCFVRGA-QRVIBDJDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 84525   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM84525 (Sulindac analogue, 22) Show SMILES CC1=C(CC(O)=O)c2cc(I)ccc2\C1=C/c1cccc(OCc2ccccc2)c1 |c:1| Show InChI InChI=1S/C26H21IO3/c1-17-23(22-11-10-20(27)14-25(22)24(17)15-26(28)29)13-19-8-5-9-21(12-19)30-16-18-6-3-2-4-7-18/h2-14H,15-16H2,1H3,(H,28,29)/b23-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institut für Molekulare Physiologie					Assay Description The kinase-catalyzed phosphorylation of poly(Glu4-Tyr) in the presence of varying concentrations of inhibitor was determined. The kinase were employ...				Chembiochem 6: 527-31 (2005) Article DOI: 10.1002/cbic.200400192 BindingDB Entry DOI: 10.7270/Q2KP80PS
					More data for this Ligand-Target Pair