BDBM84757 (11) 1H-1,2,4-triazol-3-yl-anilines 3-tBu-(C6H4) 4-Pyridine

SMILES: CC(C)(C)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1

InChI Key: InChIKey=SUKPCDABGIUDMV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 84757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM84757 ((11) 1H-1,2,4-triazol-3-yl-anilines 3-tBu-(C6H4) 4...) Show SMILES CC(C)(C)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-23(2,3)17-7-6-8-19(15-17)28-16-25-22(27-28)20-9-4-5-10-21(20)26-18-11-13-24-14-12-18/h4-16H,1-3H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.5	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM84757 ((11) 1H-1,2,4-triazol-3-yl-anilines 3-tBu-(C6H4) 4...) Show SMILES CC(C)(C)c1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1 Show InChI InChI=1S/C23H23N5/c1-23(2,3)17-7-6-8-19(15-17)28-16-25-22(27-28)20-9-4-5-10-21(20)26-18-11-13-24-14-12-18/h4-16H,1-3H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	7.5	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair