BDBM84869 Swainsonine derivative, 4
SMILES: CC(C)(C)c1ccc(cc1)C(=O)C[C@H]1CC[C@@H](O)C2[C@H](O)[C@H](O)CN12
InChI Key: InChIKey=PKZGDTMZYSPKOW-GEOHUNBWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Golgi alpha-mannosidase II (Drosophila melanogaster (Fruit fly)) | BDBM84869 (Swainsonine derivative, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.70 | -11.7 | 29 | n/a | n/a | n/a | n/a | 5.75 | 25 |
University of Toronto | Assay Description Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car... | Chembiochem 11: 673-80 (2010) Article DOI: 10.1002/cbic.200900750 BindingDB Entry DOI: 10.7270/Q2WS8RRM | |||||||||||
More data for this Ligand-Target Pair |