BDBM85019 4-Amino-5-chloro-N-(1-{4-[4-(dimethylamino)-1-piperidinyl]-4-oxobutyl}-3-methoxy-4-piperidinyl)-2-methoxybenzamide::RN 76186

SMILES: COC1CN(CCCC(=O)N2CCC(CC2)N(C)C)CCC1NC(=O)c1cc(Cl)c(N)cc1OC

InChI Key: InChIKey=YEXQFGBCXUNVRL-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HTR4 (MOUSE)	BDBM85019 (4-Amino-5-chloro-N-(1-{4-[4-(dimethylamino)-1-pipe...) Show SMILES COC1CN(CCCC(=O)N2CCC(CC2)N(C)C)CCC1NC(=O)c1cc(Cl)c(N)cc1OC Show InChI InChI=1S/C25H40ClN5O4/c1-29(2)17-7-12-31(13-8-17)24(32)6-5-10-30-11-9-21(23(16-30)35-4)28-25(33)18-14-19(26)20(27)15-22(18)34-3/h14-15,17,21,23H,5-13,16,27H2,1-4H3,(H,28,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM85019 (4-Amino-5-chloro-N-(1-{4-[4-(dimethylamino)-1-pipe...) Show SMILES COC1CN(CCCC(=O)N2CCC(CC2)N(C)C)CCC1NC(=O)c1cc(Cl)c(N)cc1OC Show InChI InChI=1S/C25H40ClN5O4/c1-29(2)17-7-12-31(13-8-17)24(32)6-5-10-30-11-9-21(23(16-30)35-4)28-25(33)18-14-19(26)20(27)15-22(18)34-3/h14-15,17,21,23H,5-13,16,27H2,1-4H3,(H,28,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	1.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									FEBS Lett 398: 19-25 (1996) Article DOI: 10.1016/s0014-5793(96)01132-5 BindingDB Entry DOI: 10.7270/Q228065Q
					More data for this Ligand-Target Pair
HTR4 (MOUSE)	BDBM85019 (4-Amino-5-chloro-N-(1-{4-[4-(dimethylamino)-1-pipe...) Show SMILES COC1CN(CCCC(=O)N2CCC(CC2)N(C)C)CCC1NC(=O)c1cc(Cl)c(N)cc1OC Show InChI InChI=1S/C25H40ClN5O4/c1-29(2)17-7-12-31(13-8-17)24(32)6-5-10-30-11-9-21(23(16-30)35-4)28-25(33)18-14-19(26)20(27)15-22(18)34-3/h14-15,17,21,23H,5-13,16,27H2,1-4H3,(H,28,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									FEBS Lett 398: 19-25 (1996) Article DOI: 10.1016/s0014-5793(96)01132-5 BindingDB Entry DOI: 10.7270/Q228065Q
					More data for this Ligand-Target Pair