BDBM85370 N-[(1H-Indol-2-yl)alkyl]acylamino Derivatives 5k

SMILES: COc1ccc2c(Br)c(CCNC(C)=O)[nH]c2c1

InChI Key: InChIKey=NTQTXEFRNIHNTF-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melatonin receptor (Homo sapiens (Human))	BDBM85370 (N-[(1H-Indol-2-yl)alkyl]acylamino Derivatives 5k) Show SMILES COc1ccc2c(Br)c(CCNC(C)=O)[nH]c2c1 Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-11-13(14)10-4-3-9(18-2)7-12(10)16-11/h3-4,7,16H,5-6H2,1-2H3,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	355	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Binding affinity towards melatonin receptor type 1B stably expressed in NIH3T3 rat fibroblast cells using 2-[125I]iodomelatonin				J Med Chem 44: 2900-12 (2001) Article DOI: 10.1021/jm001125h BindingDB Entry DOI: 10.7270/Q2QC067J
					More data for this Ligand-Target Pair
Melatonin receptor (Homo sapiens (Human))	BDBM85370 (N-[(1H-Indol-2-yl)alkyl]acylamino Derivatives 5k) Show SMILES COc1ccc2c(Br)c(CCNC(C)=O)[nH]c2c1 Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-11-13(14)10-4-3-9(18-2)7-12(10)16-11/h3-4,7,16H,5-6H2,1-2H3,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Binding affinity towards melatonin receptor type 1A stably expressed in NIH3T3 rat fibroblast cells using 2-[125I]iodomelatonin (100 pM) as radioliga...				J Med Chem 44: 2900-12 (2001) Article DOI: 10.1021/jm001125h BindingDB Entry DOI: 10.7270/Q2QC067J
					More data for this Ligand-Target Pair
Melatonin receptor (Homo sapiens (Human))	BDBM85370 (N-[(1H-Indol-2-yl)alkyl]acylamino Derivatives 5k) Show SMILES COc1ccc2c(Br)c(CCNC(C)=O)[nH]c2c1 Show InChI InChI=1S/C13H15BrN2O2/c1-8(17)15-6-5-11-13(14)10-4-3-9(18-2)7-12(10)16-11/h3-4,7,16H,5-6H2,1-2H3,(H,15,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Milano Curated by PDSP Ki Database									J Med Chem 41: 3624-34 (1998) Article DOI: 10.1021/jm970721h BindingDB Entry DOI: 10.7270/Q2T43RN6
					More data for this Ligand-Target Pair