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SMILES: SCC(Cc1ccccc1)C(=O)Nc1cc(ccn1)C(=O)Nc1ccccc1

InChI Key: InChIKey=OUZYRXPHTDLQMZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 85439   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Rattus norvegicus (Rat))		BDBM85439
PNG
(NEP inhibitor, 6s)
Show SMILES SCC(Cc1ccccc1)C(=O)Nc1cc(ccn1)C(=O)Nc1ccccc1
Show InChI InChI=1S/C22H21N3O2S/c26-21(24-19-9-5-2-6-10-19)17-11-12-23-20(14-17)25-22(27)18(15-28)13-16-7-3-1-4-8-16/h1-12,14,18,28H,13,15H2,(H,24,26)(H,23,25,27)
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Similars
Article
PubMed
n/an/a 250n/an/an/an/an/a25



R&D, Zambon Group Spa



Assay Description
Enzyme inhibition assay using neutrol endopeptiase EC 3.4.24.11 (NEP).

J Enzym Inhib 12: 155-60 (1997)


Article DOI: 10.3109/14756369709035816
BindingDB Entry DOI: 10.7270/Q2FQ9V4F
More data for this
Ligand-Target Pair