BindingDB PrimarySearch

BDBM85517 CAS_171436-38-7::SL-NH2::SLIGRL-NH2

SMILES: [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#8])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](-[#7])=O

InChI Key: InChIKey=SGPMJRPYYIJZPC-JYAZKYGWSA-N

Data: 1 KI 3 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 85517
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
F2RL1 (RAT)	BDBM85517 (CAS_171436-38-7 \| SL-NH2 \| SLIGRL-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Calgary Curated by PDSP K_i Database									J Pharmacol Exp Ther 290: 753-60 (1999) BindingDB Entry DOI: 10.7270/Q2N878BQ
The University of Calgary Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM85517 (CAS_171436-38-7 \| SL-NH2 \| SLIGRL-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Agonist activity at PAR2 (unknown origin) by cell-based assay				J Med Chem 56: 7477-97 (2013) Article DOI: 10.1021/jm400638v BindingDB Entry DOI: 10.7270/Q2NC62MG
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM85517 (CAS_171436-38-7 \| SL-NH2 \| SLIGRL-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
ACADIA Pharmaceuticals AB Curated by ChEMBL					Assay Description Agonist activity at human PAR2 expressed in HEK293T cells assessed as effect on intracellular calcium mobilization by R-SAT assay				J Med Chem 51: 5490-3 (2008) Article DOI: 10.1021/jm800754r BindingDB Entry DOI: 10.7270/Q290251P
ACADIA Pharmaceuticals AB Curated by ChEMBL					More data for this Ligand-Target Pair
Proteinase-activated receptor 2 (Homo sapiens (Human))	BDBM85517 (CAS_171436-38-7 \| SL-NH2 \| SLIGRL-NH2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Agonist activity at PAR2 in human HT-29 cells assessed as increase in intracellular calcium release				J Med Chem 56: 7477-97 (2013) Article DOI: 10.1021/jm400638v BindingDB Entry DOI: 10.7270/Q2NC62MG
The University of Queensland Curated by ChEMBL					More data for this Ligand-Target Pair